The Global Burden of Disease Study Estimates of Brazil's Cervical Cancer Burden.

Background: Cervical cancer represents an important preventable cause of morbidity and mortality in developing countries such as Brazil. Investigating temporal evolution of a disease burden in the different realities of the country is essential for improving public policies. Objective: To describe the national and subnational burden of cervical cancer, based on the estimates of the 2017 Global Burden of Disease study. Methods: Descriptive study of premature mortality (years of life lost [YLL]) and burden of disease (disability-adjusted life years [DALYs]) associated with cervical cancer among Brazilian women aged 25-64 years, between 2000 and 2017. Findings: During the study period, age-standardized incidence decreased from 23.53 (22.79-24.26) to 18.39 (17.63-19.17) per 100,000 women, while mortality rates decreased from 11.3 (11.05-11.56) to 7.74 (7.49-8.02) per 100,000 women. These rates were about two to three times greater than equivalent rates in a developed country, such as England: 11.98 (11.45-12.55) to 10.37 (9.85-10.9), and 3.75 (3.68-3.84) to 2.82 (2.75-2.9) per 100,000 women, respectively. Poorer regions of Brazil had greater rates of the disease; for instance, Amapá State in the Northern Region had rates twice as high as the national rates during the same period. Cervical cancer was the leading cause of premature cancer-related mortality (YLL = 100.69, 91.48-110.61 per 100,000 women) among young women (25-29 years) in Brazil and eight federation units of all country regions except the Southeast in 2017. There was a decrease in the burden of cervical cancer in Brazil from 339.59 (330.82-348.83) DALYs per 100,000 women in 2000 to 238.99 (230.45-247.99) DALYs per 100,000 women in 2017. Conclusion: Although there has been a reduction in the burden of cervical cancer in Brazil, the rates remain high, mainly among young women. The persistence of inequalities between regions of Brazil suggests the importance of socioeconomic determinants in the burden for this cancer.

Doencas cronicas nao-transmissiveis no Brasil: dos fatores de risco ao impacto social / Noncommunicable chronic diseases in Brazil: from risk factors to social impact

Atualmente o perfil epidemiologico do Brasil acha-se representado pelo das doencas do subdesenvolvimento versus as da modernidade. Consequentemente, o pais enfrenta dificuldades no direcionamento simultaneo de acoes para a promocao da saude que contemplem controle, tanto das doencas transmissiveis quanto das doencas cronicas naotransmissiveis (DCNT). O presente trabalho objetivou descrever a situacao epidemiologica da saude do adulto brasileiro no que tange as DCNT e apresentar dados disponiveis sobre a qualidade assistencial e o impacto social destas doencas. Para isto realizou-se uma revisao da literatura desde que foi iniciada a producao e a divulgacao de dados sobre doencas cardiovasculares, cancer e diabetes (1964-1995). Foram leventadas 153 referencias bibliograficas e usadas 97. As autoras apontam as investigacoes basicas que poderiam ser realizadas em todas as regioes do pais para subsidiar o planejamento e a administracao de estrategias populacionais para fatores de risco e para tratamento e controle das doencas cronicas naotransmissiveis no Brasil (AU)

Doencas cronicas nao-transmissiveis no Brasil: dos fatores de risco ao impacto social / Noncommunicable chronic diseases in Brazil: from risk factors to social impact

Atualmente o perfil epidemiologico do Brasil acha-se representado pelo das doencas do subdesenvolvimento versus as da modernidade. Consequentemente, o pais enfrenta dificuldades no direcionamento simultaneo de acoes para a promocao da saude que contemplem controle, tanto das doencas transmissiveis quanto das doencas cronicas naotransmissiveis (DCNT). O presente trabalho objetivou descrever a situacao epidemiologica da saude do adulto brasileiro no que tange as DCNT e apresentar dados disponiveis sobre a qualidade assistencial e o impacto social destas doencas. Para isto realizou-se uma revisao da literatura desde que foi iniciada a producao e a divulgacao de dados sobre doencas cardiovasculares, cancer e diabetes (1964-1995). Foram leventadas 153 referencias bibliograficas e usadas 97. As autoras apontam as investigacoes basicas que poderiam ser realizadas em todas as regioes do pais para subsidiar o planejamento e a administracao de estrategias populacionais para fatores de risco e para tratamento e controle das doencas cronicas naotransmissiveis no Brasil (AU)